Ever hear the term "evil albino plot device"?
Albinos have been portrayed negatively in fiction and film so often that people fear it engenders discrimination against them. Not all of them are biased, but really - when your community has been portrayed by both Gary Busey (Mr. Joshua in Lethal Weapon) and his son Jake (Joseph in Contact), that's two strikes against you right there.
Here's an example of anti-albinism, although this is SO over the top you have to wonder if anyone can really take it seriously. It's from The Life and Times of Judge Roy Bean, starring Paul Newman in the title role and Stacy Keach as Bad Bob the Albino.